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Magnesium and hypertension.

P O Wester, T Dyckner

    Journal of the American College of Nutrition
    |August 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Essential hypertension (EHT) management can be improved with magnesium (Mg). Supplementing with Mg, especially with potassium (K), may help control blood pressure (BP) and reduce cardiovascular risks.

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    Area of Science:

    • Cardiovascular Medicine
    • Clinical Nutrition
    • Public Health

    Background:

    • Essential hypertension (EHT) is a major risk factor for cerebrovascular and cardiovascular disease (CVD).
    • Current drug treatments for EHT carry risks of side effects, some impacting the cardiovascular system.
    • Non-drug interventions, including electrolyte intake modification, are gaining attention for EHT management.

    Purpose of the Study:

    • To review the evidence supporting magnesium (Mg) as an adjunct therapy for essential hypertension.
    • To explore the role of electrolytes, including sodium (Na), potassium (K), calcium (Ca), and Mg, in blood pressure (BP) regulation.
    • To provide background data for incorporating Mg into anti-hypertensive regimens.

    Main Methods:

    • Review of epidemiologic and experimental studies on electrolyte intake and BP.

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  • Analysis of existing data on the effects of Mg on EHT.
  • Examination of potential synergistic effects of Mg with other electrolytes, particularly K.

    • Main Results:

    • Decreasing Na intake is a recognized strategy for BP control.
    • Increasing K and/or Mg intake, and modifying Ca intake, have been proposed to benefit BP.
    • Evidence suggests Mg can favorably impact EHT, especially when combined with K during diuretic therapy.

    Conclusions:

    • Magnesium supplementation shows promise as part of an anti-hypertensive strategy.
    • Combined therapy with Mg and K may be particularly beneficial for patients on diuretics.
    • Further research into non-drug therapies like electrolyte management is crucial for CVD prevention.