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[Calcifications in leukokorias: ultrasonic study].

J Fernandez-Vigo, M Cordido, J Fandiño

    Journal Francais D'Ophtalmologie
    |January 1, 1987
    PubMed
    Summary

    Ultrasound revealed retinoblastoma in 43.5% of eyes with leucocoria. Calcifications were present in 85% of retinoblastoma cases, but also occurred in other conditions, highlighting diagnostic challenges.

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    Area of Science:

    • Ophthalmology
    • Medical Imaging
    • Pediatric Oncology

    Context:

    • Leucocoria, a white pupillary reflex, can indicate serious intraocular pathology in children.
    • Accurate diagnosis is crucial for timely treatment and improved outcomes.
    • Ultrasound is a valuable non-invasive tool for evaluating intraocular structures.

    Purpose:

    • To assess the utility of ultrasound in diagnosing retinoblastoma in eyes presenting with leucocoria.
    • To investigate the prevalence and significance of intraocular calcifications in retinoblastoma and other pediatric eye conditions.

    Summary:

    • An ultrasound study of 46 eyes with leucocoria found retinoblastoma in 43.5% (20 eyes).
    • Calcifications were observed in 85% (17 eyes) of retinoblastoma cases.
    • Intraocular calcifications were also present in 6 of the 26 non-retinoblastoma eyes, diagnosed as uveitis, retrolental fibroplasia, Coats disease, and retinal dysplasia.

    Impact:

    • The findings underscore that while calcifications are indicative, their absence does not rule out retinoblastoma, and their presence does not confirm it.
    • This highlights the need for comprehensive evaluation beyond calcification detection for accurate diagnosis.
    • Ultrasound findings, combined with clinical presentation, aid in differentiating retinoblastoma from other causes of leucocoria.

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