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Updated: Dec 6, 2025
Identification of Circular RNAs using RNA Sequencing
Published on: November 14, 2019
Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis
Parisa M Dana1, Mona Taghavipour2, Hamed Mirzaei1
1Research Center for Biochemistry & Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, IR Iran.
Abstract:
Endometriosis is a pathology form of endometrium that behaves in a similar way to malignancies, such as invasion and resistance to apoptosis. Circular RNAs (CircRNAs) are a class of noncoding RNAs that have several biological functions including, miRNA sponging, sequestering of proteins, enhancing parental gene expression and translation resulting in polypeptides. In this review, we highlighted the roles of circRNAs as potential diagnostic and therapeutic biomarkers in endometriosis. Moreover, we summarized the roles of circRNAs in the pathogenesis of endometriosis via different signaling pathways, such as the miRNA network and apoptosis.
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