Related Experiment Video
Updated: Dec 6, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Chronic coronary syndrome]
Stanislav Keranov1, Holger Nef1
1Medizinischen Klinik I, Innere Medizin/Kardiologie, Universitätsklinikum Gießen.
Insights
The European Society of Cardiology (ESC) updated guidelines rename stable coronary heart disease to chronic coronary syndrome (CCS). New diagnostic approaches improve pre-test probability assessment for stenosing coronary heart disease.
Area of Science:
- Cardiology
- Clinical Guidelines
Background:
- The European Society of Cardiology (ESC) introduced new guidelines in 2019.
- Stable coronary heart disease was renamed chronic coronary syndrome (CCS).
- CCS acknowledges the heterogeneity of the condition with six defined scenarios.
Purpose of the Study:
- To outline the updated diagnostic and therapeutic recommendations for chronic coronary syndrome (CCS).
- To highlight key changes in the assessment and management of patients with suspected or confirmed coronary heart disease.
Main Methods:
- Review and synthesis of the 2019 ESC guidelines for CCS.
- Emphasis on diagnostic assessment, including pre-test probability estimation.
- Evaluation of updated recommendations for imaging and invasive procedures.
Main Results:
- Introduction of dyspnea and refined clinical probability assessment for improved pre-test probability estimation.
- Enhanced role for CT angiography in detecting coronary heart disease (CHD).
- De-emphasis on routine exercise ECG for CHD detection; continued importance of invasive coronary angiography.
Conclusions:
- The updated CCS guidelines offer a more nuanced approach to diagnosis and management.
- Emphasis is placed on personalized risk assessment and the integration of lifestyle modification for prevention.
- CT angiography is now a key imaging modality, while exercise ECG is less emphasized.
Abstract:
The 2019 guidelines of the European Society of Cardiology (ESC) rename stable coronary heart disease to chronic coronary syndrome (CCS). Under CCS, six different scenarios have been defined, which take its heterogeneity into account. An important part of the current guideline plays the diagnostic assessment of the pre-test probability in the event of the possible presence of stenosing coronary heart disease. The addition of dyspnea and clinical probability as additional variables for better estimation of the pre-test probability are two important new features. Imaging techniques such as CT angiography have been significantly upgraded as diagnostic procedures for the detection of CHD, while exercise ECG is no longer routinely recommended in this regard. Invasive coronary angiography with revascularization option remains a central diagnostic and therapeutic procedure. In addition to antianginal, lipid-lowering and antithrombotic therapy, the current CCS guideline places special emphasis on prevention by means of lifestyle modification.
More Related Videos
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome I: Introduction
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome V: Nursing Management
Coronary Artery Disease I: Introduction

