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Updated: Dec 6, 2025

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A Simple Protocol for Platelet-mediated Clumping of Plasmodium falciparum-infected Erythrocytes in a Resource Poor Setting
Published on: May 16, 2013
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Acquisition of human plasminogen facilitates complement evasion by the malaria parasite Plasmodium falciparum
Timo Reiss1, Hannah I Theis1, Andres Gonzalez-Delgado2
1Division of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Aachen, Germany.
European Journal of Immunology
|October 6, 2020
Abstract:
We show that the intraerythrocytic stages of the malaria parasite Plasmodium falciparum bind plasminogen and mediate its conversion into plasmin to inactivate parasite-bound C3b. This complement evasion mechanism counteracts terminal complex formation and hence promotes parasite survival in human blood.
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