Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Negative Regulator Molecules01:23

Negative Regulator Molecules

37.7K
Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria.
37.7K
Equilibrium Conditions for a Particle01:23

Equilibrium Conditions for a Particle

2.0K
When an object is in equilibrium, it is either at rest or moving with a constant velocity. There are two types of equilibrium: static and dynamic. Static equilibrium occurs when an object is at rest, while dynamic equilibrium occurs when an object is moving with a constant velocity. In both cases, there must be a balance of forces acting on the object.
To understand the concept of equilibrium, let us first consider the forces acting on an object. When different forces act on an object, they can...
2.0K
Precipitate Formation and Particle Size Control01:16

Precipitate Formation and Particle Size Control

3.9K
In precipitation gravimetry, the precipitating agent should react specifically or selectively with the analyte. While a specific reagent reacts with the analyte alone, a selective reagent can react with a limited number of chemical species.
The obtained precipitate should be either a pure substance of known composition or easily converted to one by a simple process, such as ignition or drying. In addition, the precipitate should be insoluble and easily filterable. In general, filterability...
3.9K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

1.2K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Giant enhancement of transport driven by active fluctuations: Impact of inertia.

Physical review. E·2026
Same author

Inertia-induced mechanism for giant enhancement of transport generated by active fluctuations.

Chaos (Woodbury, N.Y.)·2025
Same author

Approach to nonequilibrium: From anomalous to Brownian diffusion via non-Gaussianity.

Chaos (Woodbury, N.Y.)·2025
Same author

Memory-induced absolute negative mobility.

Chaos (Woodbury, N.Y.)·2024
Same author

Effective mass approach to memory in non-Markovian systems.

Physical review. E·2024
Same author

Temperature anomalies of oscillating diffusion in ac-driven periodic systems.

Physical review. E·2023
Same journal

Application of ephrin-B2 loaded glycol chitosan-silk fibroin hydrogel in the treatment of diabetic refractory wounds.

Scientific reports·2026
Same journal

International expert Delphi consensus on thromboprophylaxis in metabolic and bariatric surgery.

Scientific reports·2026
Same journal

Assessing the cross-region knowledge transfer capability of selected deep learning building vectorization methods in the context of available training datasets.

Scientific reports·2026
Same journal

Feasibility and preliminary effects of outdoor versus indoor cognitive-motor therapy in women with Alzheimer's disease: A randomized single-blind pilot study.

Scientific reports·2026
Same journal

Hallmarks of social action in the vocal turn-taking of wild common marmosets (Callithrix jacchus).

Scientific reports·2026
Same journal

Role and mechanism of AOPPs-induced NOX4-mediated ferroptosis in intervertebral disc degeneration.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Dec 6, 2025

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

17.1K

Tunable particle separation via deterministic absolute negative mobility.

A Słapik1, J Spiechowicz2

  • 1Institute of Physics, University of Silesia, 40-007, Katowice, Poland.

Scientific Reports
|October 7, 2020
PubMed
Summary
This summary is machine-generated.

Scientists developed a novel particle separation method using negative mobility. This technique efficiently separates particles by size, offering a tunable solution for lab-on-a-chip devices.

More Related Videos

Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

11.4K
Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering
10:27

Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

Published on: July 10, 2016

9.5K

Related Experiment Videos

Last Updated: Dec 6, 2025

A Microfluidic-based Hydrodynamic Trap for Single Particles
10:13

A Microfluidic-based Hydrodynamic Trap for Single Particles

Published on: January 21, 2011

17.1K
Spatial Separation of Molecular Conformers and Clusters
10:37

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

11.4K
Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering
10:27

Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering

Published on: July 10, 2016

9.5K

Area of Science:

  • Physics
  • Biotechnology
  • Materials Science

Background:

  • Particle isolation is crucial in diverse fields like food safety and healthcare.
  • Current methods face challenges in efficiency and specificity for complex mixtures.

Purpose of the Study:

  • To develop an efficient and tunable particle separation strategy.
  • To explore the use of negative mobility for size-dependent particle separation.

Main Methods:

  • Simulating Brownian particles of varying sizes in a periodic potential.
  • Applying unbiased driving and a constant external force.
  • Analyzing particle movement and separation based on size and force parameters.

Main Results:

  • Demonstrated efficient particle separation through the counterintuitive effect of negative mobility.
  • Showcased tunable separation where particle size is controlled by external force parameters.
  • Identified a method where particles move opposite to the applied force based on their size.

Conclusions:

  • This negative mobility-based approach offers a novel and efficient particle separation technique.
  • The tunable nature of the method is a significant step towards developing advanced lab-on-a-chip devices.
  • Potential applications include cell sorting and disease diagnostics.