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Vagal Stimulation and Arrhythmias.
Chengzhe Liu1,2,3,4, Hong Jiang1,2,3,4, Lilei Yu1,2,3,4
1Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Journal of Atrial Fibrillation
|October 7, 2020
Summary
Autonomic imbalance contributes to arrhythmias. Vagus nerve stimulation (VNS), especially noninvasive transcutaneous VNS, shows promise for treating cardiac arrhythmias by modulating sympathetic and parasympathetic activity.
Area of Science:
- Cardiology
- Neuroscience
- Autonomic Nervous System
Background:
- Autonomic nervous system imbalance is a key factor in many arrhythmias.
- Vagus nerve stimulation (VNS) is a novel therapeutic approach for arrhythmias, leveraging anti-adrenergic and anti-inflammatory effects.
Purpose of the Study:
- To review the relationship between VNS and cardiac arrhythmias.
- To discuss advances in VNS, particularly transcutaneous VNS (tVNS), for arrhythmia treatment.
Main Methods:
- Review of current literature on VNS and cardiac arrhythmias.
- Focus on cervical and transcutaneous VNS approaches.
Main Results:
- Cervical VNS trials in heart failure patients yielded inconsistent results, suggesting a need for optimized parameters.
- Transcutaneous VNS (tVNS) offers a noninvasive alternative, stimulating the auricular branch of the vagus nerve.
Conclusions:
- Understanding VNS parameters is crucial for effective arrhythmia treatment.
- Transcutaneous VNS presents a promising, noninvasive strategy for managing cardiac arrhythmias.
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