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Updated: Dec 6, 2025
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Acute Ischemic and Hemorrhagic Stroke and COVID-19: Case Series
Poya Fatehi1, Negin Hesam-Shariati2, Morteza Abouzaripour3
1Department of Radiology, Tohid Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Insights
The coronavirus disease (COVID-19) can cause serious complications, including stroke. This study highlights five hospitalized patients with COVID-19 who experienced neurological symptoms and brain imaging abnormalities.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Background:
- The COVID-19 pandemic presents a significant global health challenge with multi-systemic complications.
- COVID-19 is associated with venous and arterial thromboembolism due to factors like immobility, inflammation, and hypoxia.
- Neurological manifestations of COVID-19 are increasingly recognized.
Purpose of the Study:
- To report cases of adult COVID-19 patients experiencing neurological complications.
- To investigate the potential link between COVID-19 infection and cerebrovascular events.
- To highlight the importance of neuroimaging in COVID-19 patients with neurological symptoms.
Main Methods:
- Retrospective case series of five adult patients hospitalized with COVID-19.
- Clinical data collection including symptoms, demographics, and family history.
- Laboratory analysis including Red Blood Cell (RBC) count.
- Cerebral Computed Tomography (CT) scans for all patients.
Main Results:
- All five patients presented with fever, chills, muscular pain, cough, and tachypnea.
- Low Red Blood Cell (RBC) levels were observed in all patients.
- Abnormal findings on cerebral CT scans were present in all patients, indicating potential brain involvement.
- Patients ranged from 20 to 55 years old, with all having had contact with family members infected with coronavirus.
Conclusions:
- COVID-19 may lead to cerebrovascular complications, including stroke.
- Brain imaging abnormalities in COVID-19 patients suggest potential damage to cerebral blood vessels.
- These findings underscore the need for vigilance regarding neurological complications in COVID-19 patients.
Abstract:
The coronavirus COVID-19 pandemic is the defining global health crisis of our time and the greatest challenge we have faced since the World Wars; it can attack several systems in the body and has high complications and mortality. COVID-19 can cause venous and arterial thromboembolism due to immobility, high inflammation, extensive intravascular blood coagulation, and hypoxia. In this study, we report 5 cases of adults with COVID-19, hospitalized in Tohid Hospital, Sanandaj, Iran. Three patients were male and two were female. The youngest patient was 20 years old and the oldest was 55 years old. All patients had at least one family member with coronavirus. Fever, chills, muscular pain, cough, and tachypnea were present in all patients. Red blood cell (RBC) was observed in all patients at a low level. Computed tomography (CT) scans of all patients showed abnormal findings in different areas of the brain. These cases indicate that COVID-19 may damage blood vessels in the brain and lead to stroke.
