Drug delivery-the increasing momentum

Area of Science:

• Pharmaceutical Sciences
• Biotechnology
• Drug Delivery Science

Background:

• Drug delivery has historically focused on enhancing exposure for small molecules and early peptide drugs.
• Significant evolution in drug modalities and delivery strategies over the past 25 years.
• Increasing diversification of therapeutic modalities in pharmaceutical and biotechnology pipelines.

Purpose of the Study:

• To highlight the critical role of drug delivery science in developing future medicines.
• To identify essential skills, capabilities, and behaviors for next-generation drug delivery scientists.
• To illustrate the necessity of integrating drug delivery science early in drug discovery and development.

Main Methods:

• Review and analysis of current trends in drug delivery and pharmaceutical R&D.
• Identification of key areas where delivery science can impact future therapeutic strategies.
• Discussion of the evolving role of drug delivery scientists in the innovation process.

Main Results:

• Drug delivery science is pivotal for enabling novel and complex drug modalities.
• Early integration of delivery science is essential for successful drug development.
• A shift in the role of drug delivery scientists from development support to early-stage innovation is evident.

Conclusions:

• The field of drug delivery science must adapt to meet the challenges of diverse and advanced therapeutic modalities.
• Proactive engagement of drug delivery scientists from the project inception is critical for future medical innovations.
• The industry must assess its readiness for this evolution to ensure the successful development of next-generation medicines.