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Laparoscopic surgery in patients with cystic fibrosis: A systematic review
Michael El Boghdady1,2, Béatrice M Ewalds-Kvist3,4
1University of Edinburgh, Scotland, Edinburgh, UK.
Insights
Laparoscopic surgery offers benefits for cystic fibrosis (CF) patients, showing good evidence as a safe surgical option. This systematic review supports its use, minimizing complications compared to open procedures.
Area of Science:
- Surgical Innovation
- Patient Outcomes
- Respiratory Medicine
Background:
- Cystic Fibrosis (CF) patients may experience fewer complications with laparoscopic surgery compared to open surgery.
- Pulmonary and cardiovascular complications remain a concern for CF patients undergoing surgery.
- Systematic review needed to evaluate laparoscopic surgery's role in CF care.
Purpose of the Study:
- To systematically review the existing literature on laparoscopic surgery in cystic fibrosis patients.
- To assess the safety and efficacy of minimally invasive surgical techniques for CF.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Comprehensive literature search across major databases (PubMed/MEDLINE, ScienceDirect, EMBASE, Google Scholar).
- Quality assessment using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria.
Main Results:
- Six studies met inclusion criteria, providing high and moderate-quality evidence.
- Interrater reliability was high (rs = .95, P = .02).
- Three quantitative and three qualitative studies were assessed and graded.
Conclusions:
- Laparoscopic surgical interventions demonstrate significant benefits for cystic fibrosis patients.
- Evidence supports laparoscopic surgery as a safe and suitable option for CF.
- Minimally invasive approaches enhance surgical outcomes in CF care.
Introduction:
Laparoscopic surgery may be advantageous for cystic fibrosis (CF) patients because it leads to fewer complications than open surgery. However, it could still lead to pulmonary and cardiovascular complications in CF patients. We aimed to systematically review the use of laparoscopic surgery in CF patients.
Methods:
A systematic review was performed in compliance with PRISMA guidelines. A literature search was performed using PubMed/MEDLINE, ScienceDirect, EMBASE, and Google Scholar, with "cystic fibrosis and laparoscopic surgery" and "cystic fibrosis and minimally invasive surgery" used as the search terms. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria were applied. The protocol was registered with the PROSPERO register.
Results:
Six studies met the predetermined inclusion criteria; accordingly, two studies provided high-quality evidence and four provided moderate-quality evidence. The interrater correlation was convincing (rs = .95, P = .02, two-tailed). Therefore, three quantitative studies and three qualitative studies were assessed and evidence-graded in accordance with the GRADE protocol.
Conclusion:
The benefits of laparoscopic surgical interventions for patients with CF were supported with good evidential value and recognized as a safe and suitable surgical option.
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