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An AIE probe for imaging mitochondrial SO2-induced stress and SO2 levels during heat stroke
Xiaopeng Yang1, Jun Tang, Di Zhang
1Green Catalysis Center, and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China. yeyong03@tsinghua.org.cn.
Chemical Communications (Cambridge, England)
|October 7, 2020
Abstract:
A probe, MITO-TPE, was developed for imaging mitochondrial SO2 with good selectivity, high sensitivity, and a fast response time. Cell imaging indicated that SO2-induced oxidative stress may cause damage to cells through O2˙- bursting. MITO-TPE has here been used to image the misregulation of SO2 levels in mitochondria during heat stroke for the first time.
