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Related Experiment Video

Updated: Jun 20, 2026

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects
07:32

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects

Published on: September 1, 2016

13.0K

Vibration threshold in non-diabetic subjects.

Svea Nolte1, Marco van Londen2, Jan Willem J Elting3

  • 1Department of Neurosurgery, University Medical Center Groningen and University of Groningen, Groningen, the Netherlands.

Plos One
|October 7, 2020
PubMed
Summary

This study identified age and height as key factors influencing vibration perception threshold (VPT) in healthy adults. The findings provide equations for individualized normal VPT values, crucial for clinical assessment and research.

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Area of Science:

  • Neurology
  • Biomedical Engineering
  • Clinical Diagnostics

Background:

  • Vibration perception threshold (VPT) measurement is vital for classifying and quantifying sensory loss.
  • The biothesiometer is a preferred tool for VPT due to low variability and minimal sensory adaptation.
  • Existing VPT values lack standardization regarding age, height, and measurement sites.

Purpose of the Study:

  • To identify determinants of vibration perception in non-diabetic individuals.
  • To establish individualized normal VPT values for clinical application.
  • To develop age- and height-specific reference ranges for VPT.

Main Methods:

  • Vibration perception threshold (VPT) measurements were taken on the big toes, insteps, lateral malleoli, and wrists.
  • 205 healthy non-diabetic subjects (52.7% male, age 21-80) participated.
  • Stepwise forward linear regression analysis identified determinants of VPT.

Main Results:

  • Age and height were significant independent determinants of VPT at the big toe (st. β = 0.51, p < 0.001 and st. β = 0.43, p < 0.001, respectively).
  • Regression equations incorporating age and height quantiles were developed.
  • The study provides formulas for calculating age- and height-specific normal VPT values.

Conclusions:

  • Age and height are crucial, unmodifiable factors influencing vibration perception.
  • The derived equations enable personalized normal VPT values for clinical practice.
  • This research supports more accurate VPT assessments in diverse populations.