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Published on: April 25, 2014
Performance of Severity Indices to Estimate Postoperative Complications of Myocardial Revascularization
Silvana Alves Dos Santos Franzotti1, Dyenily Alessi Sloboda1, Juliana Rosendo Silva2
1Universidade de São Paulo - Escola de Enfermagem, São Paulo, SP - Brasil.
Insights
The Acute Physiology and Chronic Health Evaluation (APACHE II) score effectively predicted neurological and renal complications in patients post-Coronary Artery Bypass Grafting (CABG) surgery. However, other severity indices showed limited accuracy for predicting various post-CABG complications.
Area of Science:
- Cardiology
- Intensive Care Medicine
- Medical Informatics
Background:
- Postoperative myocardial revascularization (Coronary Artery Bypass Grafting - CABG) patients in the intensive care unit (ICU) face risks of complications.
- Early identification of these risks is crucial for improving patient outcomes and reducing mortality.
Purpose of the Study:
- To evaluate the predictive performance of established severity indices for complications in post-CABG patients during their ICU stay.
Main Methods:
- A retrospective cross-sectional study analyzed electronic medical records of 366 adult patients undergoing isolated CABG.
- The study assessed the accuracy of European System for Cardiac Operative Risk Evaluation (EuroScore), APACHE II, SAPS II, and SOFA using Receiver Operating Characteristic (ROC) curves.
Main Results:
- The Acute Physiology and Chronic Health Evaluation (APACHE II) index demonstrated satisfactory performance in predicting neurological (AUC 0.72) and renal (AUC 0.78) complications.
- Identified complications included respiratory (24.32%), cardiovascular (19.95%), neurological (10.38%), hematological (10.38%), infectious (6.56%), and renal (3.55%).
Conclusions:
- APACHE II is a valuable tool for predicting specific post-CABG complications like neurological and renal issues.
- The study advises against the indiscriminate use of severity indices for predicting all potential complications in post-CABG patients, highlighting the need for tailored approaches.
Background:
Patients in the postoperative period of myocardial revascularization (Coronary Artery Bypass Grafting - CABG) surgery admitted to the intensive care unit (ICU) are at risk of complications which increase the length of stay and morbidity and mortality. Therefore, early recognition of these risks is essential to optimize prevention strategies and a satisfactory clinical outcome.
Objective:
To analyze the performance of severity indices in predicting complications in patients in the postoperative of CABG during the ICU stay.
Methods:
A cross-sectional study with retrospective analysis of electronic medical records of patients aged ≥ 18 years who underwent isolated CABG and were admitted to the ICU of a cardiology hospital in São Paulo, Brazil. The areas under the receiver operating characteristic curves (AUC) with a 95% confidence interval were analyzed to verify the accuracy of the European System for Cardiac Operative Risk Evaluation (EuroScore), Acute Physiology and Chronic Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II) and Sequential Organ Failure Assessment (SOFA) indices in predicting complications.
Results:
The sample consisted of 366 patients (64.58 ± 9.42 years; 75.96% male). The complications identified were: respiratory (24.32%), cardiovascular (19.95%), neurological (10.38%), hematological (10.38%), infectious (6.56%) and renal (3.55%). APACHE II showed satisfactory performance for predicting neurological (AUC 0.72) and renal (AUC 0.78) complications.
Conclusion:
APACHE II excelled in predicting neurological and renal complications. None of the indices performed well in predicting the other analyzed complications. Therefore, severity indices should not be used indiscriminately in order to predict all complications frequently presented by patients after CABG. (Arq Bras Cardiol. 2020; 115(3):452-459).
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