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Updated: Dec 6, 2025

A Miniaturized Glycan Microarray Assay for Assessing Avidity and Specificity of Influenza A Virus Hemagglutinins
Published on: May 29, 2016
A Designer Quest for the Achilles' Heel of Influenza
J Eduardo Fajardo1, Andras Fiser1
1Department of Systems and Computational Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA; Department of Biochemistry, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY 10461, USA.
Abstract:
Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.

