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Updated: Dec 6, 2025
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Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
Published on: November 21, 2010
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Structures from the Mesophase: MicroED Targets Crystals Extracted from LCP
Marcus Gallagher-Jones1, Jose A Rodriguez1
1Department of Chemistry and Biochemistry, UCLA-DOE Institute for Genomics and Proteomics, STROBE, NSF Science and Technology Center, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Structure (London, England : 1993)
|October 7, 2020
Abstract:
The determination of protein structures from nanocrystals grown in lipidic cubic phase (LCP) is a promising crystallographic approach. In this issue of Structure, Zhu et al. (2020) extract crystals from the dense matrix of monoolein LCP for interrogation by micro electron diffraction (MicroED) and yield a 2 Å structure of Proteinase K.
