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Validation of the Simplified Modified Rankin Scale Questionnaire
Eva Isaksson1, Per Wester2, Ann Charlotte Laska3
1Department of Neurology, Danderyd Hospital, Stockholm, Sweden and Department of Clinical Neuroscience, Neurology, Karolinska Institutet, Stockholm, Sweden, eva.isaksson@sll.se.
European Neurology
|October 7, 2020
Summary
The simplified modified Rankin scale questionnaire (smRSq) shows good validity for assessing stroke outcomes via mail. This method is a time-saving alternative to traditional face-to-face assessments, improving feasibility for large studies.
Area of Science:
- Neurology
- Clinical Trials
- Health Outcomes Research
Background:
- The modified Rankin scale (mRS) is a standard for assessing functional outcomes in stroke research.
- Traditional face-to-face mRS assessments are resource-intensive, posing challenges for large-scale studies.
- The simplified modified Rankin scale questionnaire (smRSq) offers a potentially more efficient alternative.
Purpose of the Study:
- To evaluate the validity of the Swedish version of the smRSq administered via mail.
- To compare postal smRSq results with face-to-face mRS assessments conducted 6 months post-stroke.
Main Methods:
- The study involved 108 stroke patients from the EFFECTS trial, assessed 6 months after stroke.
- Patients completed the postal smRSq, with proxy completion for 10% of participants.
- Face-to-face mRS assessments were performed by certified professionals across 4 Swedish stroke centers.
Main Results:
- Good agreement was observed between the postal smRSq and face-to-face mRS (Cohen's kappa = 0.43, weighted kappa = 0.64).
- Spearman rank correlation indicated a strong association (0.82, p < 0.0001).
- Full agreement was achieved in 55% of cases, with minor discrepancies in the remainder.
Conclusions:
- The postal smRSq demonstrates good validity as a tool for assessing functional outcomes 6 months after stroke.
- This validated questionnaire can streamline study designs, making multicenter trials and quality registers more feasible and efficient.
- Implementing the smRSq can save time and resources in stroke research.
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