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Related Experiment Video

Updated: Dec 6, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Marijuana-related Reversible Cerebral Vasoconstriction Syndrome.

Takahisa Mikami1,2, Reiichiro Obata1, Daniel I Steinberg1

  • 1Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, USA.

Internal Medicine (Tokyo, Japan)
|October 8, 2020
PubMed
Summary
This summary is machine-generated.

Recreational marijuana use can lead to serious cardiovascular and cerebrovascular events. This case study highlights reversible cerebral vasospasm syndrome (RCVS) in a chronic marijuana user, emphasizing prompt diagnosis and treatment for recovery.

Keywords:
RCVScannabinoidmarijuana

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Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Toxicology

Background:

  • The increasing legalization of recreational marijuana correlates with reported cardiovascular and cerebrovascular complications.
  • Limited research exists on reversible cerebral vasospasm syndrome (RCVS) specifically linked to marijuana use.

Observation:

  • A unique case of recurrent subcortical infarction in the watershed areas of the brain is presented.
  • The patient had a history of chronic daily marijuana use over several years.

Findings:

  • The patient exhibited bilateral anterior cerebral artery vasoconstriction.
  • Symptoms resolved rapidly with treatment, and cerebral vasoconstriction normalized on follow-up imaging.
  • These clinical and imaging findings strongly support a diagnosis of RCVS.

Implications:

  • This case underscores the potential cerebrovascular risks associated with chronic marijuana consumption.
  • Early recognition and management of RCVS in marijuana users are crucial for favorable outcomes.
  • Further research is warranted to elucidate the mechanisms and prevalence of marijuana-associated RCVS.