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[Management of mucinous tumor of appendix]

K A Shemyatovsky1, R Kh Azimov1, P S Glushkov1

  • 1Central Clinical Hospital of Russian Academy of Sciences, Moscow, Russia.

Khirurgiia
|October 8, 2020
PubMed

Insights

Low-grade mucinous tumors (MT) of the appendix are rare and can lead to peritoneal pseudomyxoma. Current classification and treatment approaches are lacking, often delaying diagnosis and worsening patient prognosis.

Area of Science:

  • Oncology
  • Gastroenterology
  • Pathology

Background:

  • Low-grade mucinous tumors (MT) of the appendix are uncommon malignancies.
  • A significant complication is peritoneal pseudomyxoma due to mucin deposition.
  • Current diagnostic and therapeutic strategies for appendiceal MT are inadequate.

Purpose of the Study:

  • To highlight the challenges in diagnosing and managing low-grade mucinous tumors of the appendix.
  • To underscore the need for improved clinical-pathomorphological classification and treatment protocols.
  • To emphasize the impact of delayed diagnosis on patient outcomes.

Main Methods:

  • Review of existing literature on appendiceal mucinous tumors.
  • Analysis of clinical presentations and diagnostic challenges.
  • Discussion of treatment complexities and prognostic factors.

Main Results:

  • Appendiceal MT are frequently discovered incidentally after appendectomy for presumed acute appendicitis.
  • Preoperative diagnosis of MT is often not possible, complicating early management.
  • Peritoneal pseudomyxoma significantly worsens the prognosis for patients with MT.

Conclusions:

  • There is a critical need for standardized clinical-pathomorphological classifications for appendiceal MT.
  • Development of unified treatment guidelines is essential for improving patient outcomes.
  • Early suspicion and diagnosis are crucial for mitigating the severe consequences of MT, such as peritoneal pseudomyxoma.
Keywords:
abscess cavity drainageacute appendicitiscecum resectionmucinous tumor

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