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A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Long-term Cardiac Maintenance Programming: A SINGLE-SITE ANALYSIS OF MORE THAN 200 PARTICIPANTS
Jeffrey W Christle1, Michaela Baumgartner, Otto Zelger
1Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California (Drs Christle, Myers, and Froelicher); Stanford Sports Cardiology, Stanford University, Stanford, California (Drs Christle and Froelicher); Department of Preventive and Rehabilitative Sports Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany (Drs Christle, Baumgartner, Zelger, Lammel, Halle, and Pressler); Institute of Medical Statistics and Epidemiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany (Dr Haller); Institute for Cardiology and Sports Medicine, German Sports University Cologne, Cologne, Germany (Dr Bjarnason-Wehrens); Department of Cardiovascular Medicine, Palo Alto Veterans Administration, Palo Alto, California (Dr Myers); Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia (Dr Hamm); Partner Site Munich Heart Alliance, DZHK (German Center for Cardiovascular Research), Munich, Germany (Dr Halle); and Kardiologie mit Herz, Private Center for Sports & Exercise Cardiology, Munich, Germany (Dr Pressler).
Insights
Long-term cardiac maintenance programs (CMPs) did not maintain functional capacity in coronary artery disease (CAD) patients. However, CMP participants showed slower deterioration compared to non-participants, despite being more deconditioned initially.
Area of Science:
- Cardiology
- Preventive Medicine
- Exercise Physiology
Background:
- Coronary artery disease (CAD) accounts for over 65% of cardiac mortality.
- Cardiac rehabilitation (CR) and subsequent cardiac maintenance programs (CMPs) aim to reduce cardiovascular risk and hospital readmissions.
- Despite guideline support, long-term efficacy data for diverse CMPs are limited.
Purpose of the Study:
- To evaluate the long-term effectiveness of cardiac maintenance programs (CMPs) in patients with coronary artery disease (CAD).
- To assess changes in functional capacity and cardiovascular risk factors in patients participating in CMPs over an extended period.
Main Methods:
- Retrospective analysis of 207 patients in CMPs, with a case-controlled subanalysis comparing 20 CMP participants to 20 matched non-participants.
- Assessments included medical history, anthropometry, blood analysis, and cardiopulmonary exercise testing.
- Follow-up duration averaged 6.3 ± 4.8 years.
Main Results:
- CMP participants experienced a reduction in peak workload and aerobic capacity over time.
- High-density lipoprotein-cholesterol levels increased significantly, while other metabolic risk factors remained unchanged.
- Matched non-participants had better baseline functional capacity and lower BMI, but no significant long-term efficacy differences were observed between groups.
Conclusions:
- Long-term CMP participation did not preserve functional capacity or the cardiovascular risk profile in CAD patients.
- Compared to matched non-participants, CMP participants, though more deconditioned at baseline, showed a slower rate of functional decline.
Purpose:
Greater than 65% of all cardiac mortality is related to coronary artery disease (CAD). Cardiac rehabilitation (CR) aims to reduce cardiovascular risk and number of hospital readmissions. Cardiac maintenance programs (CMPs) are designed to sustain or improve health after completing early CR. Although CMPs are supported by most national health guidelines, few long-term studies on these diverse programs have been performed.
Methods:
This was a retrospective repeated-measures analysis with case-controlled subanalysis. Within-subject differences for CMP participants were examined between enrollment and last clinical visit. Assessments included medical history, anthropometry, blood analysis, and cardiopulmonary exercise testing. A subset of 20 CMP participants were compared with 20 patients with CAD who chose not to participate in CMP, matched for age, sex, and follow-up duration.
Results:
A total of 207 patients (60 ± 9 yr, 16% female) were included for the primary analyses. Average follow-up was 6.3 ± 4.8 yr (range 4-20 yr). CMP participants reduced peak workload (1.76 ± 0.56 to 1.60 ± 0.58 W/kg; P < .001) and aerobic capacity (26.1 ± 6.2 to 24.6 ± 7.1 mL/kg/min; P = .003). High-density lipoprotein-cholesterol increased significantly (48 ± 12 to 51 ± 14 mg/dL; P < .001), whereas all other metabolic risk factors remained unaffected. Matched controls had higher functional capacity (2.35 ± 0.81 vs 1.56 ± 0.52 W/kg; P < .001) and lower body mass index (25.3 ± 3.6 vs 28.6 ± 3.9 kg/m2) at baseline, but no significant differences with respect to long-term efficacy were observed.
Conclusions:
Long-term participation in CMP did not result in maintaining functional capacity or cardiovascular risk profile in patients with CAD. However, compared with matched nonparticipants, CMP participants (are more deconditioned at baseline) but do not seem to deteriorate as quickly.
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