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Updated: Dec 6, 2025

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
Published on: August 17, 2022
Total body water by BIA in children and young adults with normal and excessive weight
Tej K Mattoo1, Hong Lu1, Eric Ayers2
1Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, United States of America.
Background:
Estimation of total body water (TBW) is essential for clinical care.
Objective:
Evaluation of changes in TBW by bioelectrical impedance analysis (BIA) in children and young adults with excessive weight.
Design:
Data was collected in individuals aged 3-21 years with normal (n = 202) or excessive body weight (n = 133). The BIA results from individuals with normal weight were compared with two previously published studies in children by isotope dilution methods.
Results:
Individuals with excessive weight had a higher mean TBW (27.87 L, SE 0.368) for height and age as compared to individuals with normal weight (23.95 L, SE 0.298), P<0.001. However, individuals with excessive weight had lower mean TBW (24.93 L, SE 0.37) for weight and body surface area (BSA) as compared to individuals with normal weight (26.94 L, SE 0.287), P<0.001. Comparison with two previously published studies showed no significant differences in mean TBW with one ((p = 1.00) but a significant difference with another study (p = 0.001).
Conclusions:
Individuals with excessive weight had 16.5% higher mean TBW for height and age and 7.4% lower TBW for weight and BSA as compared to normal weight individuals. Our study validates the feasibility of data collection in pediatric outpatient setting by BIA.
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