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Tackling COVID-19 Using Remdesivir and Favipiravir as Therapeutic Options

Obireddy Sreekanth Reddy1, Wing-Fu Lai2,3

  • 1Department of Chemistry, Sri Sri Krishnadevaraya University, Anantapur, 515003, India.

Chembiochem : a European Journal of Chemical Biology
|October 8, 2020
PubMed

Insights

This review examines the SARS-CoV-2 virus, the cause of COVID-19, and discusses potential treatments like remdesivir and favipiravir. It aims to guide future research in combating the pandemic.

Area of Science:

  • Virology
  • Infectious Diseases
  • Pharmacology

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has a significant global impact.
  • Current treatment strategies for COVID-19 are limited.
  • Understanding viral transmission and life cycle is crucial for developing effective interventions.

Purpose of the Study:

  • To provide an overview of the SARS-CoV-2 life cycle and transmission routes.
  • To review the therapeutic effects of remdesivir (RDV) and favipiravir (FPV) for COVID-19.
  • To serve as a reference for future research on COVID-19 treatments.

Main Methods:

  • Literature review of published data on SARS-CoV-2.
  • Analysis of the life cycle and transmission mechanisms of SARS-CoV-2.
  • Evaluation of existing studies on remdesivir and favipiravir efficacy.

Main Results:

  • SARS-CoV-2 has a defined life cycle and multiple transmission routes.
  • Remdesivir and favipiravir show potential therapeutic effects against COVID-19 based on current data.
  • Further research is needed to establish definitive treatment protocols.

Conclusions:

  • A comprehensive understanding of SARS-CoV-2 is essential for pandemic control.
  • Remdesivir and favipiravir represent promising antiviral agents for COVID-19.
  • This review highlights the need for continued investigation into effective COVID-19 therapies.
Keywords:
COVID-19favipiravirpandemicremdesivirroutes of transmission

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