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Mining the Antibody Repertoire for Solutions to SARS-CoV-2
Wenzhao Meng1, Aaron M Rosenfeld1, Eline T Luning Prak2
1Perelman School of Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Cell Host & Microbe
|October 8, 2020
Abstract:
In this issue of Cell Host & Microbe, Nielsen and colleagues sequence antibody repertoires of patients with severe COVID-19 to reveal potentially convergent features on the background of a larger, polyclonal response. Their findings suggest that, as databases improve, it may be possible to monitor virus-specific B cells after infection or vaccination using antibody sequencing.
