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Ultrasound Diagnostic Method in Vascular Dementia: Current Concepts
Antonio Siniscalchi1, Cleona Gray2, Giovanni Malferrari3
1Department of Neurology and Stroke Unit, Annunziata Hospital of Cosenza, Cosenza, Italy.
Insights
Cerebral hemodynamic changes detected by intracranial ultrasound may indicate cognitive impairment in elderly individuals. This non-invasive method aids in diagnosing vascular dementia (VaD) and stratifying cognitive decline risk.
Area of Science:
- Neurology
- Medical Imaging
- Geriatrics
Background:
- Growing interest in cerebral hemodynamics alterations linked to cognitive impairment in elderly patients with vascular risk factors.
- Vascular dementia (VaD) is a significant concern in aging populations.
- Identifying early indicators of cognitive decline is crucial for timely intervention.
Purpose of the Study:
- To review the application of intracranial ultrasound in detecting cerebral hemodynamic changes in vascular dementia (VaD) patients.
- To assess the utility of Transcranial Doppler (TCD) and transcranial duplex with color code (TCCD) in diagnosing and managing VaD.
- To highlight the potential of non-invasive ultrasound methods in cognitive impairment assessment.
Main Methods:
- Comprehensive literature search of PubMed, Embase, Cochrane library, and reference lists up to March 30, 2020.
- Inclusion of clinical studies reporting Transcranial Doppler (TCD) and transcranial duplex with color code (TCCD) parameters in VaD patients.
- Focus on non-invasive ultrasound techniques for cerebral vascular assessment.
Main Results:
- Various Transcranial Doppler (TCD) parameters have been reported in clinical studies for vascular dementia (VaD).
- The use of transcranial duplex with color code (TCCD) is less common, with most data relying on TCD.
- Transcranial Doppler (TCD) shows promise in stratifying elderly patients with early cognitive impairment.
Conclusions:
- Intracranial ultrasound is a valuable non-invasive tool for evaluating cerebral hemodynamic changes in VaD.
- Transcranial Doppler (TCD) can aid in the diagnosis and risk stratification of vascular dementia.
- Further research utilizing TCCD may enhance the understanding and management of cognitive impairment in elderly populations.
Background:
Increasing interest in identifying cerebral hemodynamics alterations as a cause of possible onset or worsening of cognitive impairment in elderly patients with vascular risk factors.
Introduction:
Intracranial ultrasound is a non-invasive, repeatable inexpensive method for recording variation of the cerebral vascular tree in physiological and pathological conditions and the diagnosis of vascular dementia (VaD).
Methods:
PubMed, Embase, Cochrane library and reference lists have been searched for articles published until March 30, 2020.
Results:
Clinical studies reported different Transcranial Doppler (TCD) parameters and subsequently transcranial duplex with color code (TCCD) in patients affected by vascular dementia. The number of studies using TCCD remains limited and most of the available data are still based on TCD. However, the use of transcranial Doppler could better stratify elderly patients with initial signs of cognitive impairment.
Conclusion:
Intracranial ultrasound employment to detect cerebral hemodynamic changes in VaD patients has been briefly discussed in this review.
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