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A RandomisEd ControLled TrIal of ChEwing Gum to RelieVE Thirst in Chronic Heart Failure (RELIEVE-CHF)

Sabine M Allida1, Sajad Shehab2, Sally C Inglis3

  • 1Neurological and Mental Health Division, The George Institute for Global Health, Sydney, NSW, Australia; IMPACCT Faculty of Health, University of Technology Sydney, Sydney, NSW, Australia.

Heart, Lung & Circulation
|October 9, 2020
PubMed

Insights

Chewing gum significantly reduced thirst in chronic heart failure patients. This intervention offers short-term and long-term relief for thirst, a common symptom in heart failure management.

Area of Science:

  • Cardiology
  • Symptom Management

Background:

  • Thirst is a prevalent and distressing symptom for patients with chronic heart failure (CHF).
  • Current interventions for thirst relief in CHF patients are limited.
  • Chewing gum has shown promise in managing thirst in patients on fluid restriction, such as those undergoing hemodialysis.

Purpose of the Study:

  • To evaluate the efficacy of chewing gum in alleviating thirst in individuals with chronic heart failure.
  • To assess the short-term (4 days) and longer-term (28 days) effects of chewing gum on thirst levels.

Main Methods:

  • A randomized controlled trial involving 71 patients with CHF on oral loop diuretics.
  • Participants were assigned to either a chewing gum group (n=36) or a control group (n=35) for two weeks.
  • Thirst levels were assessed at multiple time points: Days 1-4, Day 7, Day 14, and Day 28.

Main Results:

  • The chewing gum group demonstrated statistically significant improvements in thirst levels compared to the control group.
  • These improvements were noted at Day 4 (p=0.04) and Day 14 (p=0.02).

Conclusions:

  • Chewing gum effectively provides both short-term and long-term relief from thirst in patients with chronic heart failure.
  • This study offers valuable insights for designing future clinical trials focused on thirst management strategies in CHF.
Abstract

Keywords:
Chewing gumChronic heart failureRandomised controlled trialThirst

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