Coexistent pituitary adenoma and frontal convexity meningioma with frontal sinus invasion: A rare association

Jaskaran Singh Gosal1, Kartikeya Shukla1, Kokkula Praneeth1

  • 1Departments of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Insights

A rare case of pituitary adenoma (PA) coexisting with a frontal convexity meningioma is presented. This unusual association, with atypical meningioma location and frontal sinus invasion, has not been previously reported in medical literature.

Area of Science:

  • Neuro-oncology
  • Endocrinology
  • Neurosurgery

Background:

  • Pituitary adenomas (PA) and meningiomas are common intracranial tumors.
  • Coexistence of PA and meningioma is rare, typically occurring in the sellar/parasellar region.
  • Radiotherapy-induced meningiomas are excluded in this context.

Observation:

  • A 65-year-old female presented with a nonfunctioning pituitary adenoma.
  • She also had an associated frontal convexity meningioma with frontal sinus invasion.
  • Initial imaging findings for the meningioma were nonspecific.

Findings:

  • This case represents the first reported instance of a nonfunctioning pituitary adenoma coexisting with a frontal convexity meningioma.
  • The meningioma's location and invasion pattern were atypical.
  • The association between these two distinct tumor types in this specific configuration is novel.

Implications:

  • Highlights the importance of considering rare tumor associations in clinical diagnosis.
  • May prompt further research into potential shared etiologies or risk factors for pituitary adenoma and meningioma.
  • Challenges current understanding of tumor localization patterns for coexisting pituitary adenomas and meningiomas.

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