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Pancreatitis and Acute Liver Failure From Coricidin® HBP Intoxication
Marsha Medows1,2, Catalina Acosta1, Vivian Vega1
1Pediatrics, Woodhull Medical Center, Brooklyn, USA.
Cureus
|October 9, 2020
Summary
Adolescent recreational drug abuse of over-the-counter medications is rising. A case study highlights acute liver failure and pancreatitis after ingesting Coricidin®, a cold medicine containing acetaminophen.
Area of Science:
- Toxicology
- Adolescent Medicine
- Pharmacology
Background:
- Increasing trend of recreational drug abuse among adolescents involving over-the-counter (OTC) medications.
- OTC cold medications containing multiple active ingredients pose potential risks when misused.
Observation:
- A case presentation of an adolescent experiencing severe abdominal pain following intentional ingestion of Coricidin®.
- Coricidin® contains acetaminophen, chlorpheniramine maleate, and dextromethorphan hydrobromide.
Findings:
- The patient developed acute liver failure, a known complication of acetaminophen overdose.
- Concomitant pancreatitis was observed, which has been rarely associated with high-dose acetaminophen intake.
Implications:
- Highlights the critical need for awareness regarding the dangers of OTC medication abuse in adolescents.
- Underscores the potential for severe hepatotoxicity and other organ damage from specific ingredients like acetaminophen in misused cold remedies.
- Emphasizes the importance of monitoring and intervention strategies for adolescent substance abuse involving readily available medications.
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