Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Standardizing spirometry: problems and prospects.

E A Eisen

    Occupational Medicine (Philadelphia, Pa.)
    |April 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Standardizing pulmonary function tests for epidemiology can introduce bias. This underestimation of occupational hazards

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Deletion diagnostics for the generalised linear mixed model with independent random effects.

    Statistics in medicine·2015
    Same author

    Reply to Comment on: 'Possible pro-carcinogenic association of endotoxin on lung cancer among Shanghai women textile workers'.

    British journal of cancer·2014
    Same author

    Childhood exposure to ambient polycyclic aromatic hydrocarbons is linked to epigenetic modifications and impaired systemic immunity in T cells.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2014
    Same author

    Possible pro-carcinogenic association of endotoxin on lung cancer among Shanghai women textile workers.

    British journal of cancer·2014
    Same author

    Cotton dust, endotoxin and cancer mortality among the Shanghai textile workers cohort: a 30-year analysis.

    Occupational and environmental medicine·2013
    Same author

    Circulating adhesion molecules after short-term exposure to particulate matter among welders.

    Occupational and environmental medicine·2009
    Same journal

    Mental health issues: ethical considerations.

    Occupational medicine (Philadelphia, Pa.)·2002
    Same journal

    Ethics in the locker room: the challenges for team physicians.

    Occupational medicine (Philadelphia, Pa.)·2002
    Same journal

    Ethical issues in worker productivity.

    Occupational medicine (Philadelphia, Pa.)·2002
    Same journal

    Protecting posterity: the occupational physician's ethical and legal obligations to pregnant workers.

    Occupational medicine (Philadelphia, Pa.)·2002
    Same journal

    Genetic testing: ethical implications in the workplace.

    Occupational medicine (Philadelphia, Pa.)·2002
    Same journal

    Ethical issues in occupational disease outbreak investigations.

    Occupational medicine (Philadelphia, Pa.)·2002
    See all related articles

    Area of Science:

    • Environmental health
    • Occupational medicine
    • Pulmonology

    Background:

    • Pulmonary function tests (PFTs) and other physiologic tests are used in epidemiologic studies.
    • These tests require maximal individual effort, posing challenges to measurement validity.
    • Standardization of spirometry in epidemiologic studies is a critical but complex issue.

    Purpose of the Study:

    • To evaluate the impact of standardization on the validity of pulmonary function tests in epidemiologic research.
    • To demonstrate how current standardization methods for spirometry may introduce bias.
    • To highlight the underestimation of adverse pulmonary effects from occupational hazards due to flawed standardization.

    Main Methods:

    • Review of existing methodologies for standardizing pulmonary function tests in epidemiologic studies.

    Related Experiment Videos

  • Analysis of the challenges associated with maximal effort tests in population-based research.
  • Demonstration of bias introduced by current spirometry standardization protocols.

    • Main Results:

    • Standardization attempts for spirometry in epidemiologic studies reveal inherent biases.
    • These biases lead to an underestimation of the adverse pulmonary effects of occupational exposures.
    • The maximal effort requirement of PFTs challenges conventional measurement validity standards.

    Conclusions:

    • Current standardization of spirometry in epidemiology is inadequate and introduces bias.
    • This bias results in the underestimation of occupational lung disease risks.
    • Revising standardization protocols is crucial for accurate assessment of environmental and occupational health impacts.