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Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of

Adam S Darwich1, Thomas M Polasek2,3,4, Jeffrey K Aronson5

  • 1Logistics and Informatics in Health Care, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, SE-141 57 Huddinge, Sweden.

Annual Review of Pharmacology and Toxicology
|October 9, 2020
PubMed

Keywords:
MIPDclinical decision support systemselectronic health recordsindividualized dosingmodel-informed precision dosingpharmacokinetic/pharmacodynamic modelingsystems pharmacology

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