Advances and prospects on acid phosphatase biosensor

Acid phosphatase (ACP) is a lysosomal enzyme widely found in animals and plants. Particularly, abnormal ACP levels are often closely related to many diseases of the individual and are therefore widely used as biomarkers in clinical diagnosis. With the rapid development of precision medicine, the improvement or enhancement of the selectivity, sensitivity and broad target sample types of ACP biosensors based on the established methods has become an emerging demand for the treatment of diseases related to ACP levels. Therefore, a large number of ACP detection strategies have been used to improve these problems. In this review, the types and advantages/disadvantages of ACP detection methods were summarized and compared. According to the previous reports, the prospects and development trends of ACP detection were discussed. It was expected to provide some insights and inspiration for future research work.