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Thrombotic complications of COVID-19

Jacob Avila1, Brit Long2, Dallas Holladay3

  • 1Department of Emergency Medicine University of Kentucky, United States of America.

The American Journal of Emergency Medicine
|October 10, 2020
PubMed

Insights

COVID-19 (coronavirus disease 2019) can cause serious thrombotic complications due to a hyperinflammatory response. Emergency Medicine clinicians must recognize these vascular events to reduce patient morbidity and mortality.

Area of Science:

  • Internal Medicine
  • Cardiology
  • Vascular Medicine

Background:

  • The novel coronavirus disease 2019 (COVID-19) is linked to substantial morbidity and mortality.
  • Thrombotic complications are increasingly recognized as a significant factor in COVID-19's disease course.

Purpose of the Study:

  • This narrative review synthesizes information on thrombotic complications associated with COVID-19.
  • The review focuses on providing critical insights for Emergency Medicine clinicians.

Main Methods:

  • This study is a narrative review of existing literature.
  • The review synthesizes reported thrombotic complications and their association with COVID-19.

Main Results:

  • COVID-19-associated thrombotic complications are attributed to a hyperinflammatory response.
  • Reported complications include acute limb ischemia, aortic thrombosis, mesenteric ischemia, myocardial infarction, venous thromboembolism, stroke, and disseminated intravascular coagulation.

Conclusions:

  • Emergency Medicine clinicians require awareness of COVID-19's thrombotic complications.
  • Rapid recognition and treatment are crucial for mitigating morbidity and mortality in affected patients.
Abstract

Keywords:
COVID-19CoronavirusEmergency medicineSARS-CoV-2ThrombosisThrombotic

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