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Multıparametric Prostate Magnetic Resonance Imaging Before Radical Prostatectomy: Can it Predict Histopathology?
Mehmet Sahin1, Fuat Kizilay2, Ezgi Guler3
1Department of Urology, Ege University Hospital, Izmir 35100, Turkey. dr.mehmetsahin@hotmail.com.
Urology Journal
|October 10, 2020
Summary
Multiparametric prostate magnetic resonance imaging (mpMRI) accurately correlates with prostate cancer pathology. This study confirms mpMRI
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Multiparametric prostate magnetic resonance imaging (mpMRI) is increasingly used for prostate cancer detection.
- Histopathological correlation is crucial for validating imaging findings.
Purpose of the Study:
- To investigate the histopathological correlation of suspected prostate malignancy detected via mpMRI.
- To assess the accuracy of mpMRI in identifying key pathological features.
Main Methods:
- Retrospective analysis of 93 patients undergoing radical prostatectomy with preoperative mpMRI.
- Review of mpMRI findings (PIRADS score, extracapsular extension, seminal vesicle invasion, etc.) and pathological data (ISUP grade group, etc.).
Main Results:
- High histopathological correlation (92.07%) for lesions detected by mpMRI.
- Significant correlations found between mpMRI findings (seminal vesicle invasion, lymph node involvement) and pathological outcomes.
- Strong association between PIRADS scores and ISUP grade groups, and a negative correlation between ADC values and ISUP grade groups.
Conclusions:
- mpMRI demonstrates a high degree of accuracy in correlating with histopathological findings of prostate cancer.
- mpMRI is a valuable tool for assessing the extent and severity of prostate malignancy.
