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Diagnosis and Management of Lymphatic Disorders in Congenital Heart Disease

Benjamin Kelly1,2, Sheyanth Mohanakumar3,4, Vibeke Elisabeth Hjortdal3,4

  • 1Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark. Benjaminkelly@clin.au.dk.

Current Cardiology Reports
|October 10, 2020
PubMed

Insights

Congenital heart disease impacts lymphatic function, leading to complications like effusions. Improved diagnostics and interventions are enhancing treatment, but further research is needed for better outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Lymphatic System Research
  • Pediatric Cardiology

Background:

  • Lymphatic disorders are gaining attention due to advancements in imaging and interventions.
  • Congenital heart disease (CHD) significantly affects lymphatic system morphology and function.
  • Individuals with CHD are particularly susceptible to lymphatic complications.

Purpose of the Study:

  • To review the current understanding of lymphatic complications in individuals with CHD.
  • To summarize diagnostic approaches for these complications.
  • To outline current and potential treatment strategies.

Main Methods:

  • Literature review focusing on lymphatic complications in CHD.
  • Analysis of recent findings on pathophysiology and clinical presentation.
  • Synthesis of information on diagnostic modalities and therapeutic interventions.

Main Results:

  • Altered hemodynamics in CHD profoundly impact lymphatic system morphology and function.
  • Common lymphatic complications include chylous/serous effusions, protein-losing enteropathy, and plastic bronchitis.
  • While understanding and treatment have improved, knowledge gaps remain.

Conclusions:

  • Lymphatic complications are a significant concern in CHD patients.
  • Further research into lymphatic function, imaging, and interventions is crucial.
  • Improved understanding and targeted treatments can enhance outcomes for affected individuals.
Abstract

Keywords:
ChylothoraxCongenital heart diseaseLymphatic complicationsPlastic bronchitisProlonged effusionProtein-losing enteropathy

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