Related Experiment Video
Updated: Dec 6, 2025

Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
Septic shock caused by acute appendicitis complicated with abscess formation within mesoappendix: A case report
Yifan Man1, Shikuan Li1, Zongping Yu1
1Department of Emergency General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, PR China.
Introduction:
Acute appendicitis is the most common surgical emergency and may present with a wide variety of clinical manifestations. In rare circumstances, appendicitis can cause life-threatening complications e.g. septic shock. We present a case of septic shock caused by acute appendicitis complicated with abscess formation within the mesoappendix.
Presentation Of Case:
A 42-year-old male was presented with migratory right lower abdominal pain, accompanied by septic shock and acute kidney failure. We performed emergency appendectomy and unexpectedly observed an abscess within the mesoappendix during surgery. The patient received antibiotic therapy perioperatively. Escherichia coli and Klebsiella pneumoniae subspecies were isolated from the intraoperative pus specimen, and Bifidobacterium was isolated from his preoperative blood culture. Histopathology revealed acute suppurative appendicitis. The patient recovered uneventful and was discharged 5 days after surgery.
Discussion:
We believe that the septic shock was associated with the small abscess formation in the mesoappendix. Bacteria within the mesoappendix could enter the bloodstream through the mesoappendiceal vessel and then septic shock and kidney failure occurred sequentially. We assume that the abscess within the mesoappendix was caused by a tiny perforation from the mesoappendiceal side.
Conclusion:
The case of acute appendicitis complicated with abscess formation within mesoappendix explains one of the causes which may lead to septic shock.
Insights
A rare case of acute appendicitis with a mesoappendix abscess led to septic shock and kidney failure. Prompt appendectomy and antibiotics resulted in a full recovery, highlighting this unusual cause of severe sepsis.
Area of Science:
- Surgical Gastroenterology
- Infectious Diseases
- Critical Care Medicine
Background:
- Acute appendicitis is a common surgical emergency with diverse presentations.
- Life-threatening complications like septic shock are rare but possible.
- This case highlights appendicitis complicated by a mesoappendix abscess.
Observation:
- A 42-year-old male presented with abdominal pain, septic shock, and acute kidney failure.
- Emergency appendectomy revealed an unexpected abscess within the mesoappendix.
- Microbiological analysis identified Escherichia coli, Klebsiella pneumoniae, and Bifidobacterium.
Findings:
- Histopathology confirmed acute suppurative appendicitis.
- The septic shock was attributed to the mesoappendix abscess.
- Bacteria likely entered the bloodstream via the mesoappendiceal vessel, causing systemic illness.
Implications:
- Mesoappendix abscess is a potential cause of septic shock in appendicitis cases.
- Early surgical intervention and antibiotics are crucial for managing such severe complications.
- This presentation underscores the importance of considering atypical appendicitis complications.
More Related Videos
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Acute Pyelonephritis I: Introduction
Acute Pancreatitis II: Clinical Manifestations and Management
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Acute Pyelonephritis II: Diagnostic Studies and Management

