Septic shock caused by acute appendicitis complicated with abscess formation within mesoappendix: A case report

Yifan Man1, Shikuan Li1, Zongping Yu1

  • 1Department of Emergency General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, PR China.

Abstract

Insights

A rare case of acute appendicitis with a mesoappendix abscess led to septic shock and kidney failure. Prompt appendectomy and antibiotics resulted in a full recovery, highlighting this unusual cause of severe sepsis.

Area of Science:

  • Surgical Gastroenterology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Acute appendicitis is a common surgical emergency with diverse presentations.
  • Life-threatening complications like septic shock are rare but possible.
  • This case highlights appendicitis complicated by a mesoappendix abscess.

Observation:

  • A 42-year-old male presented with abdominal pain, septic shock, and acute kidney failure.
  • Emergency appendectomy revealed an unexpected abscess within the mesoappendix.
  • Microbiological analysis identified Escherichia coli, Klebsiella pneumoniae, and Bifidobacterium.

Findings:

  • Histopathology confirmed acute suppurative appendicitis.
  • The septic shock was attributed to the mesoappendix abscess.
  • Bacteria likely entered the bloodstream via the mesoappendiceal vessel, causing systemic illness.

Implications:

  • Mesoappendix abscess is a potential cause of septic shock in appendicitis cases.
  • Early surgical intervention and antibiotics are crucial for managing such severe complications.
  • This presentation underscores the importance of considering atypical appendicitis complications.

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
1.5K
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
308
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
298
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
545
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
297
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
178