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Updated: Jul 22, 2026

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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
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[Mitral prolapse and sudden death. A case report]
Summary
Mitral valve prolapse (MVP) and sudden cardiac death risk is debated. Mitral annular disjunction and myocardial fibrosis are key indicators of arrhythmia risk in MVP patients.
Area of Science:
- Cardiology
- Cardiac Imaging
- Electrophysiology
Background:
- The link between mitral valve prolapse (MVP) and sudden cardiac death (SCD) is controversial due to MVP's high prevalence and SCD's low incidence.
- This case highlights the importance of advanced imaging in assessing SCD risk in MVP patients.
Observation:
- A 54-year-old woman experienced sudden cardiac death, revealing bi-prolapse with low-grade leakage.
- Echocardiography and cardiac MRI identified mitral annular disjunction and inferolateral myocardial fibrosis.
Findings:
- Mitral annular disjunction and myocardial fibrosis are significant markers for ventricular arrhythmias in MVP.
- These findings are crucial for prognostic evaluation, potentially outweighing conventional clinical parameters.
Implications:
- Advanced imaging techniques are vital for identifying high-risk MVP patients.
- Systematic assessment for mitral annular disjunction and fibrosis is recommended for accurate risk stratification.
- Therapeutic strategies require careful consideration, especially for primary prevention, necessitating Heart Team consultation.
Keywords:
Arrêt cardiaque préhospitalierDisjonction annulaire mitraleFibrillation ventriculaireFibrose myocardiqueMitral annular disjunctionMitral valve prolapseMort subiteMyocardial fibrosisOut-of-hospital cardiac arrestProlapsus valvulaire mitralSudden deathVentricular fibrillationMore Related Videos
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