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Comorbidities that predict acute respiratory syndrome coronavirus 2 test positivity in Mexican Children: A

Eduardo Hernández-Garduño1

  • 1Dirección de Administración y Desarrollo de Personal, Instituto de Seguridad Social del Estado de México y Municipios (ISSEMyM), Toluca, Mexico.

Pediatric Obesity
|October 11, 2020
PubMed

Insights

Obesity and contact with COVID-19 patients increase infection risk in children. Unlike adults, COVID-19 appears less severe in children, regardless of gender or comorbidities.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Comorbidities are known risk factors for severe COVID-19 in adults.
  • The impact of comorbidities on COVID-19 susceptibility in children remains unclear.

Purpose of the Study:

  • To investigate risk factors for COVID-19 susceptibility in children.
  • To determine if specific comorbidities increase the risk of contracting COVID-19 in pediatric populations.

Main Methods:

  • A case-control study was conducted in Mexico.
  • Data collected included contact history, obesity, diabetes, hypertension, and immunosuppression.

Main Results:

  • Contact with COVID-19 patients and obesity were significant risk factors for infection in the overall sample.
  • These factors remained significant when analyzing boys and girls separately.
  • No significant differences in disease severity (pneumonia, ICU admission, death) were observed between cases and controls in children.

Conclusions:

  • Obesity is associated with increased susceptibility to COVID-19 in children, not just severe disease.
  • COVID-19 appears to be less severe in children compared to adults.
  • Further research is needed to understand the mechanisms linking obesity and COVID-19 in children.

Keywords:
Covid-19SARS-CoV-2comorbiditiesobesityrisk factor

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