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Stem Cell Transplantation Therapy: A Potential Method for Treating Cytokine Storm Syndromes Induced by COVID-19

Hayson Chenyu Wang1,2,3, Xiaojun Wang1,3, Xiao Long1,3

  • 1Department of Plastic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Cell Transplantation
|October 12, 2020
PubMed

Insights

Novel stem cell therapies show promise for treating severe COVID-19 cytokine storms. Early studies suggest stem cell transplantation is safe and potentially effective against the virus.

Area of Science:

  • * Regenerative medicine and immunology.
  • * Viral pathogenesis and host response.

Background:

  • * Coronavirus disease 2019 (COVID-19) can trigger life-threatening cytokine storm syndromes.
  • * Existing treatments for severe COVID-19 complications are limited, necessitating novel therapeutic approaches.

Purpose of the Study:

  • * To review the current landscape of stem cell-based therapies for COVID-19.
  • * To assess the preliminary safety and efficacy data of stem cell transplantation in COVID-19 patients.

Main Methods:

  • * Comprehensive review of preclinical and clinical investigations.
  • * Analysis of studies focusing on stem cell and derivatives therapy for COVID-19.

Main Results:

  • * Several studies indicate that stem cell transplantation is a safe procedure for COVID-19 patients.
  • * Preliminary evidence suggests potential efficacy in managing COVID-19 symptoms and complications.

Conclusions:

  • * Stem cell transplantation therapy presents a promising avenue for addressing severe COVID-19.
  • * Further research is warranted to fully establish the therapeutic role of stem cells in combating COVID-19.
Keywords:
COVID-19cell therapycytokine stormstem cell transplantation

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