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Updated: Dec 6, 2025

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AMH and Its Clinical Implications.

Laxmi Shrikhande1, Bhushan Shrikhande1, Aditya Shrikhande1

  • 1Shrikhande Hospital and Research Centre Pvt Ltd, Nagpur, 34/2 Abhyankar Road, Dhantoli, Nagpur, Maharashtra 440012 India.

Journal of Obstetrics and Gynaecology of India
|October 12, 2020
PubMed
Summary

Anti-Müllerian Hormone (AMH) is a key indicator of ovarian reserve and reproductive health. This review details AMH

Keywords:
Anti-Müllerian hormoneAssisted reproduction techniquesOncofertilityPCOSTargeted therapy

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Area of Science:

  • Reproductive Endocrinology
  • Gynecology
  • Oncofertility

Background:

  • Anti-Müllerian Hormone (AMH) regulates follicular maturation in women.
  • Serum AMH levels decline with age and drop significantly at menopause.
  • AMH serves as a marker for ovarian reserve and follicular pool size.

Purpose of the Study:

  • To provide a comprehensive review of the clinical applications of AMH.
  • To highlight AMH's role in diagnosing and managing various reproductive conditions.
  • To discuss AMH's utility in assisted reproductive technologies and oncofertility.

Main Methods:

  • Literature review of studies on Anti-Müllerian Hormone (AMH).
  • Analysis of AMH's physiological roles and clinical significance.
  • Synthesis of current research on AMH applications in gynecology and fertility.

Main Results:

  • AMH is a reliable marker for diminished ovarian reserve.
  • AMH levels are altered in conditions like PCOS and ovarian tumors.
  • AMH assays provide prognostic information for IVF and predict ovarian reserve post-cancer therapy.

Conclusions:

  • Anti-Müllerian Hormone (AMH) has diverse clinical applications in reproductive medicine.
  • AMH is valuable for assessing ovarian reserve, diagnosing conditions, and guiding fertility treatments.
  • AMH is a promising biomarker in oncofertility and for monitoring ovarian function.