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Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
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Risk Factors of Angiographic Recurrence After Endovascular Coil Embolization of Intracranial Saccular Aneurysms: A

Zhongbin Tian1, Jian Liu1, Ying Zhang1

  • 1Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Frontiers in Neurology
|October 12, 2020
PubMed

Insights

Recurrence after endovascular coil embolization for intracranial aneurysms is common. Low packing density of coils is an independent risk factor for aneurysm recurrence, highlighting the need for careful technique.

Area of Science:

  • Neurosurgery
  • Interventional Radiology
  • Vascular Neurology

Background:

  • Endovascular therapy for intracranial aneurysms is a common treatment modality.
  • High recurrence rates after endovascular coil embolization necessitate identification of risk factors.
  • Understanding recurrence predictors is crucial for improving long-term outcomes.

Purpose of the Study:

  • To identify risk factors associated with angiographic recurrence of intracranial aneurysms after endovascular coil embolization.
  • To evaluate the impact of various aneurysm and treatment characteristics on recurrence rates.
  • To determine independent predictors of recurrence in a large patient cohort.

Main Methods:

  • Retrospective analysis of 558 intracranial aneurysms in 504 patients treated between January 2014 and May 2015.
  • Multivariate Cox proportional hazard regression analysis was employed to assess risk factors.
  • Key variables included aneurysm size, therapy type, Raymond scale, rupture status, and packing density.

Main Results:

  • Angiographic follow-up was available for 504 patients, with 10.2% (57 aneurysms) showing recurrence.
  • Aneurysm size, therapy type, Raymond scale, rupture status, and packing density were significantly associated with recurrence.
  • Low packing density was identified as an independent risk factor for aneurysmal recurrence (p < 0.001).

Conclusions:

  • Endovascular coil embolization is an effective treatment for intracranial aneurysms.
  • Multiple factors contribute to aneurysm recurrence post-treatment.
  • Low packing density is a significant independent risk factor for recurrence, emphasizing procedural technique importance.

Keywords:
endovascular treatment (EVT)intracranial aneurysmmulticenterpacking densityrecurrence

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