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Updated: Dec 6, 2025

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Multiple catalytic sites in MOF-based hybrid catalysts for organic reactions
Yu Wang1, Liyu Chen1, Chun-Chao Hou1
1AIST-Kyoto University Chemical Energy Materials Open Innovation Laboratory (ChEM-OIL), National Institute of Advanced Industrial Science and Technology (AIST), Sakyo-ku, Kyoto 606-8501, Japan. q.xu@aist.go.jp.
Abstract:
Hybrid catalysis provides an effective pathway to improve the catalytic efficiency and simplify the synthesis operation, but multiple catalytic sites are required. Catalysts with multiple functions based on/derived from metal-organic frameworks (MOFs) have received growing attention in organic synthesis due to their wide variety and outstanding designability. This review provides an overview of significant advances in the field of organic reactions by MOF-based hybrid catalysts with emphasis on multiple catalytic sites and their synergies, including inherent sites on host frameworks, sites of MOF composites and metal sites in/on MOF-derived hybrid catalysts.
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