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Updated: Dec 6, 2025

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

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Non-invasive imaging techniques to assess myocardial perfusion

Olivier Villemain1,2,3, Jérôme Baranger2, Zakaria Jalal4,5

  • 1Division of Cardiology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto , Toronto, ON, Canada.

Expert Review of Medical Devices
|October 12, 2020
PubMed

Insights

Noninvasive imaging techniques are advancing for assessing coronary artery disease and myocardial perfusion, offering crucial insights beyond traditional methods. New ultrasound and hybrid approaches show promise for future diagnostics.

Area of Science:

  • Cardiovascular Imaging
  • Medical Diagnostics
  • Physiology

Background:

  • Coronary artery disease remains a leading global cause of death.
  • Invasive methods like coronary angiography are the gold standard for assessing myocardial perfusion.
  • Noninvasive imaging is increasingly vital for therapeutic decisions and prognostication.

Purpose of the Study:

  • To review recent advancements in noninvasive imaging for myocardial perfusion assessment.
  • To discuss the diagnostic capabilities and limitations of various imaging modalities.
  • To highlight emerging technologies in the field.

Main Methods:

  • Utilizes various noninvasive imaging modalities: echocardiography, coronary CT angiography, MRI, and nuclear imaging.
  • Enables assessment of coronary artery anatomy and microcirculation.
  • Quantifies myocardial perfusion at rest and during stress.

Main Results:

  • Noninvasive techniques provide valuable data on coronary artery anatomy and microcirculation.
  • Quantitative assessment of myocardial perfusion is achievable with current technologies.
  • Technological evolution is enhancing the role of noninvasive imaging.

Conclusions:

  • New ultrasound technologies and hybrid imaging approaches represent the future of myocardial perfusion assessment.
  • Noninvasive imaging plays a critical role in guiding patient management and prognosis.
  • Continued innovation is crucial for improving cardiovascular disease diagnosis.
Abstract

Keywords:
Cardiac imagingcoronary artery diseasemyocardial perfusion

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