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Bruch Membrane Opening Minimum Rim Width Changes During Scleral Lens Wear.
1Montreal University School of Optometry, Montreal, QC, Canada.
Eye & Contact Lens
|October 12, 2020
Summary
Scleral lens wear significantly reduces Bruch membrane opening minimum rim width (BMO-MRW). This change, potentially linked to intraocular pressure, was not influenced by corneal factors or refractive error.
Area of Science:
- Ophthalmology
- Optometry
- Biomedical Engineering
Background:
- Scleral lenses (SLs) are used to correct vision in various ocular conditions.
- Understanding the impact of SL wear on optic nerve head parameters is crucial for patient safety.
- Bruch membrane opening minimum rim width (BMO-MRW) is a key indicator of optic nerve health.
Purpose of the Study:
- To evaluate the change in BMO-MRW during scleral lens wear.
- To investigate potential correlations between BMO-MRW changes and ocular parameters.
Main Methods:
- Twenty healthy subjects underwent diurnal measurements of intraocular pressure (IOP), corneal biomechanics, central corneal thickness (CCT), and BMO-MRW using optical coherence tomography (OCT).
- Measurements were repeated over 6 hours with and without a scleral lens.
- Statistical analysis included two-way ANOVA and multiple linear regressions.
Main Results:
- Scleral lens wear resulted in a statistically significant decrease in BMO-MRW over 6 hours (-8 μm, P<0.001).
- The diurnal variation of BMO-MRW was significantly different with SL wear compared to without (-3.35 μm, P=0.029).
- BMO-MRW changes did not significantly correlate with corneal rigidity (CR), CCT, or refractive error.
Conclusions:
- Scleral lens wear induces a significant decrease in BMO-MRW.
- The observed BMO-MRW reduction may be related to changes in intraocular pressure.
- Further research is necessary to determine the clinical significance of these optic nerve head changes during scleral lens wear.
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