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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Dec 6, 2025

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Intraocular Pressure Reduction after Phacoemulsification: A Matched Cohort Study.

James A Carolan1, Liyan Liu2, Stacey E Alexeeff2

  • 1Department of Ophthalmology, Kaiser Permanente, San Rafael, California.

Ophthalmology. Glaucoma
|October 12, 2020
PubMed
Summary

Phacoemulsification surgery can lower intraocular pressure (IOP) in glaucoma patients. This study found a modest IOP reduction of approximately 1-2 mmHg, with fewer patients needing glaucoma medications post-surgery.

Keywords:
Cataract surgeryElectronic health recordGlaucomaIntraocular pressure

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Cataract Surgery Outcomes

Background:

  • Phacoemulsification is associated with intraocular pressure (IOP) reduction in various ocular conditions.
  • The magnitude of IOP change following phacoemulsification has shown variability in previous studies.

Purpose of the Study:

  • To evaluate the effect of phacoemulsification on intraocular pressure (IOP) in patients with glaucoma and related conditions.
  • To compare IOP changes and the need for glaucoma procedures between surgical and non-surgical groups.

Main Methods:

  • Retrospective cohort study matching 16,169 surgical patients with non-surgical controls.
  • Analysis of electronic medical records for IOP, medication use, and glaucoma procedures over 36 months.
  • IOP measurements utilized Goldmann applanation tonometry and other tonometric methods.

Main Results:

  • Surgical patients demonstrated lower average IOP throughout 36 months post-procedure compared to the non-surgical group.
  • A significant IOP reduction of 1.21 mmHg was observed in the surgical group, particularly in patients with ocular hypertension or high baseline IOP.
  • Fewer surgical patients required glaucoma medications, and the need for selective laser trabeculoplasty decreased, though glaucoma surgery odds increased for primary open-angle glaucoma.

Conclusions:

  • Phacoemulsification offers a modest IOP reduction (1-2 mmHg) in patients with preoperative IOP below 20 mmHg.
  • The observed IOP reduction is less pronounced than reported in prior referral-based studies.
  • Surgeons can anticipate a moderate IOP lowering effect and potential decrease in medication burden following phacoemulsification.