Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

1.7K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.7K
Teratogenicity01:07

Teratogenicity

3.8K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.8K
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

509
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
509
Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

Pharmacokinetics: Drug–Food and Drug–Viral Interactions

96
A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
96
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

673
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
673
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

100
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
100

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reflex Testing for Hepatitis D Infection: A Unique Opportunity to Reduce Hepatitis D-Related Chronic Liver Disease Deaths in Australia.

The Medical journal of Australia·2026
Same author

Editorial: Low-Level Viraemia in Chronic Hepatitis B-A Benign State or Missed Opportunity?

Alimentary pharmacology & therapeutics·2026
Same author

Temporal Patterns in Preterm Birth Subtypes and Perinatal Survival, 2000-2023: Population-Based, Repeated Cross-Sectional Time-Series.

BJOG : an international journal of obstetrics and gynaecology·2026
Same author

Evaluation of fingerstick blood point-of-care testing of hepatitis B DNA for enhanced hepatitis B treatment decision making: a diagnostic accuracy study.

Journal of clinical microbiology·2026
Same author

Severe Idiopathic Secretory Diarrhoea With a Profound Sustained Response to Somatostatin Analogues: A Case Report.

Case reports in gastrointestinal medicine·2025
Same author

The effect of prenatal psychotropic drug exposures on obstetric complications: 19-year population-based study.

The British journal of psychiatry : the journal of mental science·2025

Related Experiment Video

Updated: Dec 6, 2025

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
09:11

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

21.2K

Viral hepatitis and pregnancy.

Norah A Terrault1, Miriam T Levy2, Ka Wang Cheung3

  • 1Keck School of Medicine, University of Southern California, Los Angeles, USA. Terrault@usc.edu.

Nature Reviews. Gastroenterology & Hepatology
|October 13, 2020
PubMed
Summary
This summary is machine-generated.

Viral hepatitis in pregnancy poses risks to both mother and infant. Acute hepatitis A and E are most dangerous, while HBV, HCV, and HDV risks include chronic disease and mother-to-child transmission.

More Related Videos

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

10.2K
Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

4.2K

Related Experiment Videos

Last Updated: Dec 6, 2025

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
09:11

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

21.2K
A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
10:28

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks

Published on: June 26, 2020

10.2K
Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

4.2K

Area of Science:

  • Hepatology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Viral hepatitis management in pregnancy requires careful consideration due to unique viral characteristics and potential impacts on maternal and fetal health.
  • Five distinct hepatitis viruses (A, B, C, D, E) present varied epidemiological profiles, chronicity potential, and treatment responses.
  • Pregnancy influences viral hepatitis course, and conversely, viral infections affect maternal and infant outcomes, including mother-to-child transmission (MTCT).

Purpose of the Study:

  • To review the epidemiology of viral hepatitis in pregnant individuals.
  • To examine the impact of pregnancy on viral hepatitis progression and vice versa.
  • To discuss maternal and infant outcomes, including MTCT, associated with viral hepatitis during pregnancy.

Main Methods:

  • This is a review article.
  • Literature review on viral hepatitis in pregnancy.
  • Synthesis of current knowledge on epidemiology, clinical course, and outcomes.

Main Results:

  • Acute hepatitis A virus and hepatitis E virus infections during pregnancy pose the greatest risk to maternal health and fetal well-being.
  • Hepatitis B virus, hepatitis C virus, and hepatitis D virus risks are primarily linked to maternal liver disease severity and MTCT.
  • Prevention of MTCT for HBV and HCV is crucial for reducing the global burden of chronic viral hepatitis.

Conclusions:

  • Viral hepatitis in pregnancy necessitates individualized management strategies.
  • Understanding viral-specific risks and MTCT is essential for optimal maternal and infant care.
  • Effective MTCT prevention strategies must address local healthcare and socioeconomic factors.