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Water-Borne Isocyanate-Free Polyurethane Hydrogels with Adaptable Functionality and Behavior.

Maxime Bourguignon1, Jean-Michel Thomassin1, Bruno Grignard1

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Macromolecular Rapid Communications
|October 13, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a novel, non-isocyanate method for creating diverse polyurethane hydrogels in water at room temperature. This green chemistry approach avoids toxic reagents, offering safer and more accessible hydrogel synthesis for various applications.

Keywords:
cyclic carbonateshydrogelsnon-isocyanate polyurethanespolyhydroxyurethanes

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Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Green Chemistry

Background:

  • Traditional polyurethane hydrogel synthesis relies on toxic isocyanate chemistry.
  • There is a need for safer, more sustainable methods for producing polyurethane hydrogels.

Purpose of the Study:

  • To develop a facile and direct non-isocyanate route for synthesizing a wide range of polyurethane hydrogels.
  • To explore the preparation of anionic, cationic, and neutral hydrogels under mild conditions.

Main Methods:

  • Synthesis of hydrosoluble polymers bearing cyclic carbonates via free radical polymerization.
  • Non-isocyanate reaction of these polymers with diamines in water at room temperature.
  • Investigation of hydrogel formation at varying pH and reinforcement using in-situ generated CaCO3 particles.
  • Preparation of thermoresponsive hydrogels using specialized polymers.

Main Results:

  • A diverse library of polyurethane hydrogels (anionic, cationic, neutral) was successfully synthesized using a non-isocyanate pathway.
  • Hydrogel properties, including gel time and storage modulus, were influenced by pH.
  • Reinforced and thermoresponsive hydrogels were achieved through formulation modifications.
  • The synthesis proceeded efficiently under mild conditions without catalysts.

Conclusions:

  • A versatile and environmentally friendly method for producing various polyurethane hydrogels has been established.
  • This non-isocyanate approach offers significant advantages over traditional methods, reducing toxicity and improving accessibility.
  • The findings open new avenues for the development and application of advanced hydrogel materials.