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Related Concept Videos

Linearization and Approximation01:26

Linearization and Approximation

51
Linearization is a mathematical technique used to approximate complex, nonlinear functions with simpler linear models in the vicinity of a chosen reference point. The method is based on the idea that, although a function may be difficult to evaluate exactly, its behavior near a specific input value can often be closely approximated by the tangent line at that point. This approach is particularly useful when small deviations from a known value are involved.Consider the square root function, for...
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Vesicular Tubular Clusters01:45

Vesicular Tubular Clusters

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After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi.
With the help of motor proteins such...
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Linear Circuits01:17

Linear Circuits

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A linear circuit is characterized by its output having a direct proportionality to its input, adhering to the linearity property, which encompasses the principles of homogeneity (scaling) and additivity. Homogeneity dictates that when the input, also referred to as the excitation, is multiplied by a constant factor, the output, known as the response, is correspondingly scaled by the same constant factor. For instance, if the current is multiplied by a constant 'k,' the voltage likewise...
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Vesicular Trasport: Endocytosis, Transcytosis and Exocytosis01:18

Vesicular Trasport: Endocytosis, Transcytosis and Exocytosis

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Vesicular transport is a cellular process that encompasses the engulfment of particles or dissolved substances by cells. It involves endocytosis, transcytosis, and exocytosis.
Endocytosis is a cellular mechanism that involves the inward folding of the cell membrane to create vesicles that capture and transport large drug molecules. This process comprises two distinct methods: pinocytosis (often referred to as "cell drinking") and phagocytosis (often referred to as "cell...
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Linear Momentum00:55

Linear Momentum

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The term momentum is used in various ways in everyday language, most of which are consistent with the precise scientific definition. Generally, momentum implies a tendency to continue on course—to move in the same direction; we tend to speak of sports teams or politicians gaining and maintaining the momentum to win.  Momentum is also associated with great mass and speed and is often considered when talking about collisions. For example, when rugby players collide and fall to the...
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Ecological Succession02:17

Ecological Succession

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Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
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Related Experiment Video

Updated: Jan 25, 2026

Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis
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Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis

Published on: October 18, 2024

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Differentiating vesicular linear lichen planus and lichen striatus.

M Katz, L Weinrauch

    Cutis
    |August 1, 1987
    PubMed
    Summary

    This case study highlights vesicular linear lichen planus, an uncommon skin condition. We discuss its unique presentation and differential diagnoses for better clinical recognition.

    Area of Science:

    • Dermatology
    • Clinical Case Reports
    • Rare Skin Diseases

    Background:

    • Lichen planus is a common inflammatory condition affecting skin and mucous membranes.
    • Typical lichen planus presents with pruritic, purple, polygonal papules and plaques.
    • Atypical variants, such as the linear or vesicular form, are less frequently encountered.

    Observation:

    • A 62-year-old woman presented with a distinctive vesicular linear rash.
    • The morphology and distribution of the lesions were key diagnostic features.
    • Clinical examination revealed vesicles arranged in a linear pattern on the skin.

    Findings:

    • The case confirmed a diagnosis of vesicular linear lichen planus.
    • Differential diagnoses considered included other blistering dermatoses and inflammatory conditions.

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  • Histopathological examination may be crucial for definitive diagnosis of unusual lichen planus variants.
  • Implications:

    • Recognizing this rare presentation is vital for accurate diagnosis and appropriate management.
    • Understanding the differential diagnosis aids in excluding other serious conditions.
    • This case contributes to the literature on the varied clinical spectrum of lichen planus.