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[Severe skin and soft tissue infections. An update]

Eleonora R Cunto1, Ángel M Colque2, María Paula Herrera3

  • 1Hospital de Infecciosas Francisco J. Muñiz, Buenos Aires, Argentina.

Medicina
|October 13, 2020
PubMed

Insights

Severe skin and soft tissue infections demand complex surgical care due to high risks. Prompt diagnosis, antibiotics, and surgical debridement are crucial for better outcomes, especially with resistant bacteria.

Area of Science:

  • Infectious Diseases
  • Surgical Infections
  • Microbiology

Background:

  • Severe skin and soft tissue infections (SSTIs) are associated with significant morbidity and mortality.
  • The incidence of SSTIs ranges from 0.3 to 5 cases per 10,000 individuals annually.
  • Common causative agents include Streptococcus pyogenes, Staphylococcus aureus, anaerobes, and gram-negative bacilli.

Purpose of the Study:

  • To review the management of severe skin and soft tissue infections.
  • To highlight the importance of prompt diagnosis and treatment strategies.
  • To discuss emerging therapeutic options for multidrug-resistant infections.

Main Methods:

  • Literature review on severe skin and soft tissue infections.
  • Analysis of common etiologic agents and their resistance patterns.
  • Evaluation of current and novel treatment approaches.

Main Results:

  • Effective management relies on early diagnosis, empirical antibiotic therapy, and repeated surgical debridement.
  • Multidrug-resistant organisms pose a growing challenge in SSTI treatment.
  • New therapeutic strategies show promise for combating resistant infections.

Conclusions:

  • A multidisciplinary approach is essential for optimal management of severe SSTIs.
  • Timely and aggressive intervention can significantly improve patient outcomes.
  • Continued research into novel treatments is vital for addressing resistant pathogens.
Keywords:
cellulitisdiagnosisfasciitismyositistreatment

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