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Published on: May 30, 2013
Financial incentives to increase pediatric HIV testing: a randomized trial
Irene N Njuguna1,2,3, Anjuli D Wagner2, Jillian Neary1
1Department of Epidemiology.
Insights
Financial incentives significantly increased pediatric HIV testing rates among caregivers living with HIV. Higher incentive amounts led to faster testing times, demonstrating their effectiveness in improving child HIV testing outcomes.
Area of Science:
- Public Health
- Global Health
- Pediatric Infectious Diseases
Background:
- Financial incentives are known motivators for adult health behaviors like HIV testing.
- Limited data exists on the efficacy of financial incentives for pediatric HIV testing, a critical intervention to prevent child mortality.
- Urgent need to identify effective strategies for timely pediatric HIV diagnosis.
Purpose of the Study:
- To evaluate the effectiveness of varying financial incentives on increasing pediatric HIV testing rates among caregivers living with HIV.
- To assess the impact of financial incentives on the time to pediatric HIV testing.
Main Methods:
- A five-arm unblinded randomized controlled trial was conducted in 19 HIV clinics in Western Kenya.
- Adults living with HIV with children aged 0-12 years of unknown HIV status were randomized to receive $0, $1.25, $2.50, $5, or $10.
- Child HIV testing within two months was the primary outcome, with time to testing also analyzed. The study was registered under NCT03049917.
Main Results:
- Caregivers receiving higher incentives showed increased pediatric HIV testing uptake. Specifically, the $10 incentive arm had significantly higher testing completion rates (61%) compared to the $0 arm (34%).
- A dose-response relationship was observed, with significantly faster time to testing in the $5 and $10 incentive groups compared to the control group.
- The $10 incentive group showed a relative risk of 1.80 for testing completion, and hazard ratios of 1.95 and 2.42 for faster testing in the $5 and $10 arms, respectively.
Conclusions:
- Financial incentives are effective in improving pediatric HIV testing among caregivers living with HIV.
- The study highlights the potential of financial incentives as a public health tool to enhance pediatric HIV testing and reduce mortality.
- Tailoring incentive amounts based on observed effectiveness can optimize pediatric HIV testing strategies.
Background:
Financial incentives can motivate desirable health behaviors, including adult HIV testing. Data regarding the effectiveness of financial incentives for HIV testing in children, who require urgent testing to prevent mortality, are lacking.
Methods:
In a five-arm unblinded randomized controlled trial, adults living with HIV attending 19 HIV clinics in Western Kenya, with children 0-12 years of unknown HIV status, were randomized with equal allocation to $0, $1.25, $2.50, $5 or $10. Payment was conditional on child HIV testing within 2 months. Block randomization with fixed block sizes was used; participants and study staff were unblinded at randomization. Primary analysis was intent-to-treat, with predefined primary outcomes of completing child HIV testing and time to testing.
Results:
Of 452 caregivers, 90, 89, 93, 92 and 88 were randomized to $0, $1.25, $2.50, $5.00, and $10.00, respectively. Of those, 31 (34%), 31 (35%), 44 (47%), 51 (55%), and 54 (61%) in the $0, $1.25, $2.50, $5.00, and $10.00 arms, respectively, completed child testing. Compared with the $0 arm, and adjusted for site, caregivers in the $10.00 arm had significantly higher uptake of testing [relative risk: 1.80 (95% CI 1.15--2.80), P = 0.010]. Compared with the $0 arm, and adjusted for site, time to testing was significantly faster in the $5.00 and $10.00 arms [hazard ratio: 1.95 (95% CI 1.24--3.07) P = 0.004, 2.42 (95% CI 1.55--3.79), P < 0.001, respectively).
Conclusion:
Financial incentives are effective in improving pediatric HIV testing among caregivers living with HIV.
Registration:
NCT03049917.
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