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A Core Outcome Set for Pediatric Critical Care

Ericka L Fink1, Aline B Maddux2, Neethi Pinto3

  • 1Department of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA.

Critical Care Medicine
|October 13, 2020
PubMed

Insights

A core outcome set was developed for pediatric critical care to improve outcomes for children. This multinational, multistakeholder-recommended set includes cognitive, emotional, physical, and overall health domains for better clinical and research programs.

Area of Science:

  • Pediatric critical care research
  • Outcome measurement in child health
  • Multisite clinical studies

Background:

  • Children surviving critical illness face risks of new or residual health conditions.
  • A standardized, evidence-informed core outcome set is needed for pediatric critical care.
  • This study aimed to establish a multinational, stakeholder-recommended core outcome set for pediatric critical care.

Framework:

  • A modified Delphi electronic survey was used, involving 333 stakeholders.
  • Two survey rounds assessed 45 specific outcomes across six global domains.
  • Consensus was defined by outcomes scoring >90% critical and <15% not important.

Implementation:

  • Multinational survey with participants from six continents.
  • Stakeholders included clinicians, researchers, and family/patient advocates.
  • A virtual consensus conference finalized the core outcome set components.

Implications:

  • The developed Pediatric Intensive Care Unit (PICU) core outcome set provides a standardized framework.
  • This resource is intended for clinical and research programs to enhance outcomes for critically ill children and their families.
  • An extended set includes additional outcomes suggested by families, enhancing comprehensiveness.
Abstract

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