Eccrine porocarcinoma: case report and review of the literature
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Updated: Sep 22, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Michele Grieco1,2, Francesco Simonacci3,2, Eugenio Grignaffini1,2
1Division of Plastic Surgery, Department of Surgical Sciences, University of Parma, Parma, Italy.
Abstract:
Eccrine porocarcinoma is a rare skin cancer that originates from the acrosyringium of eccrine sweat glands. From the clinical point of view the differential diagnosis with other skin cancers such as basal cell carcinoma and squamous cell carcinoma it is often impossible, only the histopathologic features can lead to the definitive diagnosis. Eccrine porocarcinoma can arise from a previous poroma or de novo, it may recur after surgical excision and cause lymph node and visceral metastasis. There are no international guidelines for treatment or follow-up of patients. The aim of this work was to present a rare case of eccrine porocarcinoma of the scalp successfully treated in our clinic and to extrapolate from the international literature the main clinical and histopathological features of eccrine porocarcinoma and the various experiences regarding the types of treatment.
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