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Related Concept Videos

PPE Use in Healthcare Settings I: Donning01:22

PPE Use in Healthcare Settings I: Donning

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Donning PPE must be completed before contact with the patient. This process protects from infectious agents. The sequence and action included in each donning are critical, and the steps must be systematic to avoid exposure to pathogens. The institutional policy also needs to be followed while donning PPE. The pre-donning preparations are gathering equipment, inspecting the PPE equipment for tears, holes, or damage, removing jewelry, removing any garments below the elbows, and tying the hair...
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PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

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The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
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Personal Protective Equipment01:20

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Personal protective equipment (PPE) is unique clothing or equipment worn by an employee to minimize or prevent exposure to infectious agents. PPE creates a barrier between the employee and the infectious materials. PPE must be readily available in the patient care area. PPE includes gloves, gowns and aprons, masks and respirators, goggles, face shields, shoes, and headcovers:
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Dosage Regimen: Individualization01:24

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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Drug Therapy01:28

Drug Therapy

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
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Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

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Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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APD or CAPD: one glove does not fit all.

Athanasios Roumeliotis1, Stefanos Roumeliotis1, Konstantinos Leivaditis1

  • 1Division of Nephrology and Hypertension, 1st Department of Internal Medicine, AHEPA University Hospital, School of Medicine, Aristotle University of Thessaloniki, 1, St. Kyriakidi Street, 54636, Thessaloníki, Greece.

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Automated Peritoneal Dialysis (APD) offers lifestyle benefits and can achieve dialysis targets, but its superiority over Continuous Ambulatory Peritoneal Dialysis (CAPD) remains debated. Patient choice is key for implementing APD.

Keywords:
Automated peritoneal dialysis (APD)Continuous ambulatory peritoneal dialysis (CAPD)Fast transportersPatient selection

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Area of Science:

  • Nephrology
  • Renal Medicine

Background:

  • Automated Peritoneal Dialysis (APD) use is rising, particularly in developed nations.
  • This increase is linked to advancements in cycler technology, lifestyle advantages, and achieving dialysis adequacy and ultrafiltration goals.

Purpose of the Study:

  • To evaluate the benefits and drawbacks of Automated Peritoneal Dialysis (APD) compared to Continuous Ambulatory Peritoneal Dialysis (CAPD).
  • To determine the optimal use cases and patient selection for APD.

Main Methods:

  • Comparative analysis of APD and CAPD based on existing literature and clinical observations.
  • Review of patient compliance, physiological impacts, and treatment outcomes associated with both modalities.

Main Results:

  • APD is advantageous for fast transporters and in assisted peritoneal dialysis (PD) settings.
  • Potential benefits include improved patient compliance, reduced intraperitoneal pressure, and possibly lower peritonitis rates.
  • Drawbacks include higher costs, potential for faster decline in residual renal function, inadequate sodium removal, and sleep disturbances.

Conclusions:

  • While APD shows specific advantages, particularly for fast transporters, its overall medical superiority over CAPD is controversial.
  • APD should be accessible to all initiating PD, with patient preference being the primary factor for its adoption.